After 7 days in high-density cultures, primary human chondrocytes showed well-developed cartilage nodules with viable cells and well-developed and organized cell organelles, such as rER, mitochondria, glycogen granules, free cytoplasmic ribosomes, Golgi apparatus.
With antibody treatment, these aggressive, disorganized malignant breast tumor cells reverted to well organized, polarized cells that formed ascini in culture.
Within the cell clusters/niches, cell layer appeared well organized with established cell-to-cell communication, abundant cytoplasmic extensions, and a perfect adaptation to the underlying material microporosity and topography.
sie also interacts with the genes coding for the actin organizers Filamin and Profilin and, in the absence of sie function, F-actin is less well organized and nurse cells frequently fuse.
Histopathology analysis of the infected lungs demonstrated the formation of well organized granulomas comprising epithelioid cells, multinucleated giant cells and foamy macrophages surrounded by large numbers of lymphocytes.
The microtubule network within the cell cytoplasm was also visualized, but with less intensity, and was seen to be well organized and surrounding the cell nucleus.
It was of interest that in one year-old mice (n = 4), the leukocyte aggregates after immunofluoresence staining for B-cells (blue), T-cells (red) and FDC (green), were often seen to be well organized, with well defined T-cell and B-cell zones.
M. × giganteus culm tissues were well organized, consisting of several cell types, including sclerenchyma fiber (Sf) surrounding the vascular bundles, parenchyma (Par), protoxylem vessel (Pxv), metaxylem vessel (Mxv), sieve tube (St) and companion cell (Com).
Multiple types of cells are well organized in BBB, which include endothelial cells, astrocytes, and pericytes (Zhao et al., 2015; Attwell et al., 2010; Knowland et al., 2014; Armulik et al., 2010; Dalkara and Alarcon-Martinez, 2015).
MCF10A cells cultured in 3D Matrigel proliferate and go on to form well organized polarized acini and cells that detach from the basement membrane undergo anoikis favoring lumen formation [39].
Immunostaining with a pan-cytokeratin antibody revealed that MOSE-E cells have a well organized intermediate filament network extending throughout the cells, whereas the intermediate filament network in MOSE-L cells is composed of short filamentous structures that do not radiate throughout the cell in a organized manner (Figure 3A, last column).
