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In summary, we demonstrate that our experimental model is not only feasible and reproducible, but also mimics well observations in humans and could therefore be considered as a suitable pre-clinical rat animal model for the further study of the behavior of orthotopic CRC liver metastases following the stimulus of PH.
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Even though this function represents well the observations in many cases, it yields a slip that increases indefinitely with time and must be truncated ad hoc.
This common approach helps to bring out the similarities between the two processes and the predictions of the model agree well with observations in both cases.
On the contrary, the unpaired CS/US protocol was ineffective in producing trace conditioning memory in our animals (Fig. S1), which is highly consistent with the well documented observations in literature [e.g. see 3], [7], [8], [11].
They refer mainly to a total of 22 inter- and intra-organizational group meetings, as well as observations in waiting rooms.
This fits well with observations in mouse that MTF1 is essential for embryonic organ development, whereas targeted deletion post-partum is not lethal [ 22, 23].
On the other hand, the findings match very well with observations in rat tendon cells obtained from postnatal tissue [24] and more recently with observations from human fibroblasts in culture [25].
Even so, the observed strength of the associations between Qol self- and proxy reports in our study were only low to moderate, corresponding well to observations in the general population between student and parents [ 36].
Indeed, AKT, ERK1/2 and p70S6K got activated in all cell lines, which was revealed by simulations as well as observations in graphical analyses (Table 1, Figures 4, 5, 6).
The findings from this study, as well as observations in rodent and human systems, suggest a model for how mutation of the zebrafish dbt gene leads to abnormal swimming.
That is, proportions of essential genes in mouse singletons and duplicates are similar, in contrast to the well-known observations in other model organisms [ 1, 3].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com