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However, these large datasets make data analysis challenging thus we opted to collapse thousands of single cell measurements into a 'per well' measurement.
While any summarization results in the loss of information, the 'per well' measurement includes cell morphology information that is unavailable to traditional high-throughput screening, and the image data can be later mined for further insights.
As well, measurement of preterm infants provides weight, head circumference and length measurements while ultrasound only provides estimates of these measures.
We found limited temporal variation by season and by decade within each of the five aquifer types over the well measurement period, as well as across the land use classifications used in our analysis.
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The methods used to characterize waste collection systems were based on data collection from suppliers as well measurements in the field.
Aberrant well measurements and discontinuities are problematic for all methods.
For a small number of individuals with multiple well measurements, we considered variability in well measurements in a sensitivity analysis using a time-weighted well concentration rather than an arithmetic average to predict serum PFOA concentrations [see Supplemental Material (doi 10.1289/ehp.1002503)].
Results are expressed as means ± SEM from at least four independent well measurements for each concentration of toxin.
All the raw images, library metadata, single cell measurements, and well measurements are publicly available through our openBIS based publication portal.
Further research is needed to determine how well measurements of corn and soybean herbicides in residential dust samples predict human exposure.
Model validation was conducted by using groundwater well measurements and surface (canal) water levels provided by the St . Johns Water Management District and U.S. Geological Survey (USGS) sources.
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