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In spite of the well known difficulty to obtain plasma sprayed coatings containing SiC, characterisation results evidenced that the used process did not affect the phase composition.
This flexibility can be exploited to handle robustly vacuum states, which is a well known difficulty of standard Roe's method, while maintaining Roe's low diffusivity.
A well known difficulty arises from the high intensity acoustic noise produced by gradient switching in echo-planar imaging (EPI), as well as in other fMRI sequences more similar to conventional MR sequences.
The well known difficulty of taking into account edge effects during such measurements poses further questions as well as the effect of the density of occupation, and the seasonal variations due to clothing.
A well known difficulty of zebrafish immunological research is the paucity of mAbs against zebrafish blood cells, which excludes use of fluorescent activation cell sorting, a technique sometimes used in other fish species to sort for cells of interest [45].
The distinct cross-reactivity with sera positive for antibodies against yellow fever virus is a well known difficulty for all common serological assays and is also mentioned in the instruction leaflet of the commercial test kits [ 11].
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Given the well known difficulties in realising 4% savings a year, leaping to 6-76-7% heroic.
Fine manipulation with an industrial arm encounters many well known difficulties.
But this too faces well known difficulties in the context of modern physics (see, for example, Earman 1989).
The noise level is increased before 1930, most likely due to well known difficulties in maintaining the base level of recordings.
The well known difficulties in obtaining the optical access inside the impeller have been overcome by allowing the internal flow planes to be illuminated by the laser light sheet or shot by the CCD camera through the moving blade vanes.
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