SMN is well known to assist in assembly of U snRNPs, which is central to splicing, in the cytoplasm and to recruit U snRNPs into the nucleus (Pellizzoni et al, 2002).
Convective self-assembly, well known for producing highly ordered monolayer structures, has been used in this study to create novel surface patterns using the binary mixture of colloids.
Because short read assembly is well known to be computationally intense when the data size is large, we did a pre-screening homology search prior to the assembly and only assembled the reads of a same species that are homologous to known Csl proteins.
It is well known that after manufacture and assembly the input parameters of the structure do not exactly correspond to the designed values.
De novo assembly is well known to producing a high fraction of false chimeras [ 25, 26] and we found an effective method to control for these by checking the amount of sequence shared by fusion partner genes at the breakpoint (Additional file 1: Material 1, Additional file 1: Figure S2).
It is well known that the part fabrication variation, coupled with the part's deformation during the assembly process, is one of the main factors affecting the assembly quality.
However, problems in short read data assembly are also well known [ 69].
For instance, extracellular Ca2+ and protein kinase C (PKC) signalling are well known to be involved in desmosome assembly.
Box 1 It is well known and accepted that the spindle assembly checkpoint helps the formation of Mad2 Cdc20, and subsequent MCC APC/C complexes through the activity of Mad1 Mad2.
Since these transition states are frequently targeted in therapies for inflammatory disease and cancer, we characterized the dynamic regulation of enhanceosome assembly using the well known transcriptional co-activator protein P300.
