Sentence examples similar to well established variants from inspiring English sources

Consistent with our previous analyses, 6 7 we primarily applied the approach using a genetic risk score based on 32 well established BMI variants rather than a single locus to test for interaction.

We examined the interaction between frequency of fried food consumption (both at home and away from home) and a genetic risk score based on 32 well established genetic variants associated with BMI in relation to BMI and obesity in women and men from two prospective cohorts: the Nurses Health Study and Health Professionals Follow-upp Study.

As a more practical point, the TEA and VariationHunter programs produce reports in non-standard formats, rather than the well established standard variant call format (VCF) [ 31], an issue for data communication and downstream analysis.

It has been well established that genetic variants in the fatty acid desaturase genes (FADS1 and FADS2) associate with the fatty acid composition in adult populations [1].

This approach mapping reads, remove duplicates, and calling variants is well established for obtaining variants from exome data.

It is well established that genetic variants can alter mRNA folding [ Shen et al., 1999], which in turn can influence function [ Halvorsen et al., 2010].

Genomic medicine often relies on well established catalogs of specific variants and variant databases to substantiate conclusions about rare variants.

To investigate whether the better glucose tolerance phenotype in the offspring of long-lived individuals is due to lack of genetic variants associated with type 2 diabetes, we analyzed 15 well established type 2 diabetes variants in the Leiden Longevity Study [ 13] for their association with familial longevity.

It is well established that copy number variants (CNVs) contribute to the etiology of these disorders.

Although testing for chromosomal disorders and monogenic Mendelian disorders is well established, testing for common variants is still controversial.

Although the relevance of mutations in several DNA repair genes (BRCA1, BRCA2, TP53, PTEN, PALB2, BRIP1) in breast cancer susceptibility have been well established, the association of variants in other genes, potentially accounting for the remaining familial clustering, is not well defined.