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The HDS has well established validity and reliability [ 35].
The KPS scale is widely used to evaluate functional status in patients with cancer and has well established validity and reliability.
Cognition: Cognitive function will be measured using CogState, a computerised test battery with well established validity and sensitivity to detect subtle cognitive change in community cohorts [ 32- 35].
Finally, while the recognition task we used to measure interpretative bias has well established validity, its reliability has yet to be formally examined.
While the reliability of the hop test scores has been well established, validity studies have revealed low sensitivity rates in detecting functional limitations using the hop index (the ratio or percentage of limb performance).
This version of the recognition task has been widely used to assess change in interpretive bias due to Cognitive Bias Modification procedures and has well established validity (e.g., Mackintosh et al., 2006; Mathews & Mackintosh, 2000; Salemink, van den Hout, & Kindt, 2007; Yiend, Mackintosh, & Mathews, 2005).
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A set of well-known instruments with established validity and reliability was selected for psychometric testing in this study.
It has established validity and reliability [ 48].
While the analytic validity of the gene expression component of the Oncot ype DX® RS is well established, the clinical validity – i.e the calibration and discrimination of the recurrence predictions of the Oncot ype DX® RS - has not been published.
1 2 In psychiatry, the validity of some diagnostic codes, such as schizophrenia 13 14 and bipolar disorder, 15 has been well established, while the validity of other diagnoses such as tic disorders, including TS and OCD, have yet to be studied.
Externalizing behavior was measured with the Youth Self-Report [CBCL YSR; 53], which has well established reliability and validity.
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