Sentence examples for well established validation from inspiring English sources

As much as validation of analytical methods is quite well established, validation of experimental design or bioinformatics analysis is still in its infancy.

Although the efficacy and safety of bortezomib is well established, validation of its benefits in patients of different ethnic backgrounds is warranted.

Target capture and deep sequencing is a well established method for validation of large numbers of putative SNVs detected in WGS data [ 24– 26].

The use of benchmark datasets is well established for the validation of analysis methods for gene expression (Cope et al., 2004; Holloway et al., 2006) and genotyping (Lin et al., 2008) microarrays.

While rapid prototyping systems are well established for early functional validation, they will assume an additional role in the SEA-Design Chain in validating architectural models used for the ECU's microcontroller specification.

While such an analysis is not as powerful for assessing the true predictive performance of a model, it is well established that k-fold cross-validation provides an estimate of the predictive performance, and k = 5 is considered a reasonable compromise between bias and variance for this estimate [ 45- 47].

While well established protocols are available for the validation of self-report based assessment tools there is no consensus on how to validate tools for observational assessment.

DEM methodology has been well established but there is a lack of detailed validation of DEM models to experimental data and methods to calibrate and scale-up DEM models to attain accurate predictions and results.

The actual challenge for an automated annotation tool is to annotate newly identified sequences or genomes in addition to the validation of the tool on the well established annotations of highly studied proteins.

Our instrument underwent detailed tests for validation in independent data sets, following well established recommendations [ 39, 43, 49].

The CDVs of some of the precommercial hs-cTnI assays used for the validation of our findings may be considered less well established.