Sentence examples for well established status from inspiring English sources

The finding of two B. intermedia accessions completely embedded in B. vulgaris and fully resistant to DBM was a surprise and could be a chance effect, considering genetic distinctness of B. intermedia in previous molecular investigations [ 37], near lack of flea beetle resistance in the species [ 6], and the well established status of B. intermedia [ 39].

It is well established that ER status correlates well with response to tamoxifen treatment.

It's well established that socioeconomic status and other dental clinical variables have a negative impact on OHRQoL [ 3, 45].

It is well established that intracellular redox status or oxidative stress plays an important role in cancer cells apoptosis [ 21].

It is now well established that the redox status of the cell has a key role in cell fate.

It is well established that a defective status of the DNA repair machinery (especially BRCA1/2 genes) correlates with a better response to platinum-based therapy [ 30].

While the IHC-based assay for ER positivity is well established, we use ER status prediction as a base case for the classifiers.

In early stage breast cancer it is well established that the metastatic status of the SLN is an important prognostic parameter, but an optimal method of SLN analysis is still not available.

The majority of human promoters belong to the high-CpG class of promoters, for which it is well established that the methylation status of the surrounding CpG islands has a direct influence on the promoter activity unmethylated CpG islands in the promoter region correspond to active promoters, whereas heavily methylated mCpG islands correspond to inactive promoters [ 18].

It has been well established that the methylation status of CpG islands directly affects the DNA-protein interactions by eliminating the otherwise occurring sequence specific binding of the transcription factors whereas inducing the DNA-bindings of members of the methyl-CpG binding protein family (MBD).

As the interaction between volemic status and RMs is not well established, we hypothesized that volemic status would potentiate possible deleterious effects of RMs on lung and distal organs in a model of extrapulmonary lung injury induced by sepsis.