Sentence examples similar to well established sequence from inspiring English sources

Before reaching a critical mass and becoming well established, sequence-based data will need to be confirmed by other methods.

It is well established that sequence divergence at the interspecific level has an inhibitory effect on sexual recombination [ 49- 52].

The association between polymorphism and gene order variability is not surprising: it is well established that sequence evolution and genome rearrangement are positively correlated (Begun and Aquadro 1992; Shao et al. 2003; Xu et al. 2006; Koonin 2009), even if the reasons behind this are still object of a heated debate (Begun and Aquadro 1992; Charlesworth et al. 1993; Nachman 2001).

While the capacity for differential expression of proteins with alternative substrate affinities is well established, corresponding sequence has only been obtained for a high-affinity arginine transporter in L. donovani [ 23], an amastigote-specific transporter in L. amazonensis [ 26] and a polyamine permease in L. major [ 27].

Small RNAs such as miRNA and siRNA are now well established as sequence-specific regulators of gene expression at the mRNA level [1].

While the link between inflammation and colon cancer is well established, the temporal sequence of the inflammatory response in relation to tumorigenesis has not been characterized.

Moreover, it is now well established that mtDNA sequences are often incorporated into nuclear genomes in diverse taxa, including humans and other primates [ 4, 5].

It is well established that raw sequencing data would drastically overestimate the number of unique clones and the only way to fully overcome this would be to apply sophisticated experimental and bioinformatic methods for error correction (see Shugay et al. [ 21 ] for more information).

This mapping allowed us to directly predict individual protein functions and protein families by comparing the sequence to well established families from known genome sequences.

It is also well established that detailed individual sequence alignments (i.e. as available through the TIGR and Gramene genome browsers) are informative in terms of establishing sequence similarities on a gene by gene basis.

New generation sequencing has become affordable and exom sequencing well established standard technology.