In contrast to the well established requirement for the participation of either viral 3′TLS or host-tRNAs in the assembly of RNA-containing virions in brome mosaic virus (BMV; Choi, Y, G., Dreher, T. W., Rao, A. L. N. 2002. tRNA elements mediate the assembly of an icosahedral RNA virus. Proc. Natl. Acad. Sci. 99, 655 660), CCMV CP does not require the presence of viral TLS in cis or in trans.
Wings with a bs14 mutant posterior compartment exhibited a transformation of all cell types to vein fate - due to a well established requirement for SRF in vein patterning that is independent of Mal (Fig. 1F) [8].
The single-award approach is contrary to well established procurement requirements and is out of sync with industry's multi-cloud strategy, which promotes constant competition, fosters rapid innovation and lowers prices," he said, echoing the language in the complaint.
The regular and specific education of staff members and mechanisms to control their performance are well established and mandatory requirements for all laboratories working under rules defining a good manufacturing practice but have so far not been systematically applied for immunomonitoring of clinical samples.
Scenarios are a well established approach to describe functional requirements, uncovering hidden requirements and trade-offs, as well as validating and verifying requirements.
The engineering and servicing requirements are well established to deal with its high toxicity and low flammability.
While the requirement for Vav SH2, SH3, CH, and PH domains for Vav function in TCR signaling is well established [43], [47], [50], [51], the requirement for the GEF activity remains controversial [30], [34], [50], [52], [53].
Normovolemic hemodilution is a well established blood conservation technique, reducing the requirement for allogeneic red cell transfusions [ 8].
CYP2C9 is subject to a genetic polymorphism affecting its activity, and the fact that this polymorphism contributes to individual anticoagulant dose requirement is now well established, although its effect on phenprocoumon metabolism is less pronounced than that on either warfarin or acenocoumarol [ 2, 4- 7].
(ADA-B; USPSTF-B) CF patients have nutrition requirements which are well established (62– 62).
Sex-specific energy budgets are a well established concept owing to different reproductive requirements, especially in highly migratory pelagic fish [ 78- 80].
