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Although Ca2+ is a well established regulator of membrane fusion events, little is known about its role in these processes during autophagy.
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EETs are P450-derived metabolites of arachidonic acid and are well established regulators of cardiovascular and renal function [16].
These genes are well established regulators of energy homeostasis and play important roles in determination of food preferences [ 35- 46].
The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases
Since we observed that CDCA induced ATP release, we hypothesized that the intracellular Ca2+ responses could be due to effect of released ATP on P2 receptors, which are well established regulators of stimulated Ca2+ influx and/or Ca2+ release in pancreatic ducts.
PKA is a well established negative regulator of Hh signaling that directly phosphorylates Gli2 and Gli3 to promote their processing by the proteasome [10], [16].
IFNγ is a well established negative regulator of airway allergic immune responses [ 21].
NR1D1 and PPARγ-binding protein are functionally related to PPARγ, a well established positive regulator of adipogenesis and lipid storage.
Although well established as regulators of transcription factors during T cell activation, the MAPK pathways have also been implicated in control of amino acid [36] [38] and glucose [24], [25] utilization in other cell types.
Heat shock factors of the classes A and B are well established as regulators of thermal and non-thermal stress responses in plants; however, the role of class C HSFs is unknown.
BiP is also an established regulator of ER stress transducers.
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