Good convergent validity could also be demonstrated for the FQLP with AQ and EQ, which are well established questionnaires regarding symptoms of AS.
However, as the efficiency of those programmes has not been well established, especially regarding early prevention of recurrence of LBP, more evidence is needed [ 42, 43].
Taken together, these data are consistent with the well established hypothesis regarding the linkages between ABA and plant mitochondrial functionality [ 55- 57].
The tool has been validated against well established questionnaires regarding disability and psychological parameters and it psychometric performance was shown to be similar to that of the longer Orebro Musculoskeletal Screening Questionnaire [ 15, 29].
While the phIGFBP-1 presence in cervical secretion in predicting preterm labor is well established, data regarding its similar role in predicting term or post-term delivery are limited.
Aside from well established concerns regarding the use of sodium bicarbonate, there is evidence from animal models of lung and systemic sepsis that the anti-inflammatory and protective effects of hypercapnic acidosis are lost with buffering.
In HER2-overexpressing breast cancer, which is associated with a high recurrence rate and poor outcome (Slamon et al, 1987; Paik et al, 1990; Kallioniemi et al, 1991; Boss et al, 2003), trastuzumab-based therapies are well established and regarded as a standard therapy (Slamon et al, 2001; Pegram et al, 2004).
The role in apoptosis of some of these proteins has been well established, in particular regarding chaperone HSP70 and HSP90 [26].
Although the involvement of MBD proteins in gene silencing is well established, new facets regarding the links between DNA methylation, MBD proteins and gene transcription are emerging.
Cognitive behavioural approaches are well established with regards to their clinical efficacy for anxiety and depression in cancer and individualised approaches are more effective than groups [ 29].
