Twist1 and Twist2 (Twist1–2) are two transcription factors, members of the basic helix-loop-helix family, that have been well established as master transcriptional regulators of embryogenesis and developmental programs of mesenchymal cell lineages.
Pursue hands-on training opportunities that allow you to train under an established master colorist.
SOX9 is well established as the master regulator of chondrogenesis and a factor required for the maintenance of the immature chondrocyte phenotype, and thus a potential target of RBPjk-dependent Notch function in cartilage development.
Thus far, only PGC-1α (peroxisome-proliferator-activated receptor-γ co-activator 1α), the original member of the PGC-1 family of transcriptional co-activators, has been well established as a master regulator of mitochondrial biogenesis in adipocyte and muscle cell differentiation (Puigserver et al., 1998; Wu et al., 1999; Lehman et al., 2000).
Reassuringly, well established players in the master regulatory pathways of senescence (for example p53) have also been identified in these screens [ 24, 25].
It is well established that spo0A is the master regulator for sporulation events in both bacilli and clostridia [ 5, 34].
It is well established that the deletion of this master NER gene in yeast essentially abrogates excision and repair of UV lesions by NER in the genome [ 86].
It is well established that PPARα serves as a master regulator of fatty acid catabolism, which is also apparent from our data [ 22, 40].
As a tomb sculptor, Stone was well established in London by 1622, and he became master mason to the crown in 1632.
The established masters bore names like Beaux, Burne-Jones, Degandand Monet.
But the two collectors were not interested only in work by established masters.
