Although the effect of tumor complexity on perioperative outcome measures is well established, the impact of renal pelvic anatomy on perioperative outcomes remains poorly defined.
Although the role of high-dose radiotherapy on neurological impairment is well established, the impact of other treatments is less clear.
Although its role for sampling non-palpable breast lesions is already well established, the impact of VABB with 11-Gauge (11G) needle on health-related quality of life (HRQoL) has never been investigated.
Associations between diabetes mellitus (DM) and pancreatic ductal adenocarcinoma (PDAC) are well established; however, the impact of DM on perioperative morbidity and mortality after PDAC resection is unclear.
It is well established for the impact of Cry1Ab on O. nubilalis larva, that growth inhibition data are much more sensitive than mortality data (i.e., EC50 values are about one order of magnitude lower than LC50 values) [14].
Although the association between exposure to asbestos and malignant mesothelioma (particularly malignant pleural mesothelioma) has been well established, the health impact of environmental exposure (EE) to asbestos has been less studied.
The diagnosis and complications associated with heart failure (HF) have been very well established to adversely impact an individual's physical and psychosocial well-being, and interventions such as cognitive behavioral techniques have demonstrated potential positive benefits among patients with HF.
Racial disparities in blood pressure control are well established; however the impact of low health literacy (LHL) on blood pressure has garnered less attention.
While the consequences of vitamin D or estrogen deficiency in women have been well established, the skeletal impact of these (partial) age-related deficiencies in men remains to be clarified.
Although the benefits of controlling reservoirs of human parasite infection with therapeutic drugs are intuitive, appealing, and well established, only limited impact can be expected where high transmission levels persist 18, 46, 50, 53 and the dangers of applying strong selection pressure for drug resistance upon robust parasite populations are also obvious.
