Sentence examples for well established functional from inspiring English sources

Since we found a strong correlation between the number of shared targeting viral proteins and pathways the underlying host proteins co-appear in, the virus potentially tailored its surface to attack the host cell along well established functional pathways.

Authors' response: Yes, there is no elevated frequency of p53 response elements (RE) in Alu elements, but the number of well established functional p53 REs, 160, is probably too small to make final conclusions.

Because of overlapping expression patterns and the well established functional redundancy within the Src family, identification of the roles played by individual family members in chondrocytes will be a major challenge and will probably require detailed analyses of knockout mice for single or multiple Src family genes.

Furthermore this preliminary analysis was only based on the essential genes of B. subtilis, and it is well established that functional ubiquity does not equate to gene ubiquity: a same function could be essential in other clades, but performed by a gene of a completely different descent.

Although it is well established that functional MTs preserve a sequence with 20 invariants cysteines, no studies have thus far established the polymorphic status of the remaining residues.

The distinctiveness of each group was also evident when comparing other well established sperm functional parameters (viability, capacitation status, acrosome integrity and chromatin integrity; data not shown) although differences were more significant for MT-G staining.

It is well established that functional coronary collateral arteries are of paramount importance in the prognosis of CAD.

First, it is not well established whether functional Ca 2+ channels are present in the nuclear envelope in neurons, and if they can indeed release Ca 2+ into the nucleoplasm.

4 8 Well-designed high-impact publications have established functional interactions between miRNAs and key mechanisms implicated by GWAS in IBD, notably T helper cell (Th 17 mediated inflammation and autophagy.

Based on the established functional data, SHOX2 as well as SHOX2 targets represent excellent candidates for human arrhythmias.

The functions of IsiA in these complexes were not well established, and many functional propositions were deduced exclusively from the physiological analysis.