Sentence examples for well established first from inspiring English sources

The following roles of telomeres are well established: First, telomeres can regulate the lifespan of cells (Harley et al, 1990; Allsopp et al, 1992; Levy et al, 1992; Bodnar et al, 1998).

First-generation technologies are well established, second-generation technologies are entering markets, and third-generation technologies heavily depend on long-term research and development commitments, where the public sector has a role to play.

By this time, fortunately, his parallel career in poetry was well established; his first collection, Once Bitten, Twice Bitten, came out in February 1961 (also, coincidentally, the year he married his first wife, Jannice Henry).

It was not until the Foxes had been well established in first place and the Paris-born midfielder had been called for the national squad that people really started to take notice of him.

Imatinib is now well established as first-line therapy for metastatic/inoperable GISTS and the National Institute for Health and Clinical Excellence (NICE) approved its use for patients with KIT-positive unresectable/metastatic GISTS in 2004 (National Institute for Clinical Excellence, 2004; Heinrich, 2010).

In past decades, it became well established as first-line therapy for many types of arrhythmias, including atrioventricular (AV) nodal re-entrant tachycardia (AVNRT), circus movement tachycardia (CMT), and cavotricuspid isthmus (CTI -dependent atrial flutter (AFl), and as therapeutiCTI -dependenthe treatrial oflutterl fibrillAFlon (andb), asrial therapeutic (AT), and ventricular tachycardia (VT).

As recently reviewed (Crown et al, 2002; Nabholtz et al, 2002), the anthracyclines are well established in first-line chemotherapy for metastatic breast cancer, and anthracycline-containing regimens have been shown to confer higher response rates and longer survival overall than nonanthracycline combinations such as cyclophosphamide plus methotrexate and 5-FU (CMF) (A'Hern et al, 1993).

It is now well established that first-line treatment should include a platinum compound (Harries and Gore, 2002), with carboplatin being the drug of choice, having been shown to have equivalent efficacy but less toxicity than cisplatin (Alberts, 1995; Du Bois et al, 1999; Ozols et al, 2003).

The well-posedness of the model is established first.

The tone of this series had been well established through the first four games.

More than 100 architectural offices from around the world answered the call, including some rather well established companies, but first prize was eventually awarded to "riza3".