It is well established that neonates experience pain [ 3, 4].
It is well established that conditions experienced during early development contribute critically to phenotypic variation (e.g. [1], [2]) ultimately affecting life-history strategies, reproductive success and survival.
It has been well established that HCWs experienced significant stress during infectious epidemics [ 5- 9].
It is now well established that prior test experience can alter behavioural baselines and attenuate/abolish the anxiolytic efficacy of benzodiazepines in the elevated plus-maze paradigm.
While it is well established that women prisoners experience high levels of socioeconomic disadvantage, the policy discussion around short term, remand, and fine default imprisonments has not extended to consider the potential implications of these for children with incarcerated mothers.
Like S. cerevisiae, H. polymorpha is characterized by simple cultivation mode in inexpensive growth media, well established genetic tools and experience on industrial cultivation and scaling-up.
First, although the efficacy of immunomodulatory therapy appeared to be lower than for FTY720 in TRANSFORMS and parenteral administration is associated with poorer compliance than for oral preparations, the safety profiles of IFN-β and glatiramer acetate are well established by lengthy postmarketing experience.
It is well established that uncontrollable adverse experiences lead to increased distress, but the role of client control during psychological interventions such as exposure is less clear.
For example, it is well established that patients having experienced an acute myocardial infarction should receive an aspirin within 24 hours of hospital admission.
Standards for assessing the pituitary stalk size are not well established, and are based on experience rather than age-appropriate measurements.
Single-centre experience from well established intestinal rehabilitation centres comprises only up to 16 children 13, 14.
