As in experimental fungal diseases there are a few but well established examples of antibodies whose protective value is modulated depending on the isotype [33], [38], we wondered whether, and to what extent, the anti-β-glucan IgM was also protective.
While there are many examples of HGT between prokaryotes [ 20], well established examples of HGT from prokaryotic into metazoan organisms are relatively few, with some examples revealed to be artifacts of improper analysis [ 13, 21- 23].
Well established examples of non-exponential population growth apply to global demography (super-exponential or hyperbolic case; q=2 [ 10]) and some molecular replicator systems (sub-exponential or parabolic case; q=1/2 [ 11]).
Inflammatory bowel disease (IBD) is a well established example in that patients with IBD have an increased risk for the development of CRC [ 4].
The roles of copy number variant CNVs and loss of heterozygosity in tumourigenesis are well established, for example, in the form of oncogene amplification.
It is well established, for example, that a bout of strep throat can set off rheumatic fever, an autoimmune disorder.
The health benefits are well established; for example, a middle-aged man can halve his risk of dying prematurely by walking two miles a day.
The existence of anthropogenic climate change is now well established (for example, see [ 24, 25]) thus we do not attempt to summarize this research here.
Well established for example through the recent Planck satellite measurements.
After high-speed trains between Paris and Lyons became well established, for example, commercial flights all but disappeared.
