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Because the turning points from enabling to limiting are not well established, effective electrolyte replacement currently depends as much on the rider's development of a specific dosage regimen (amounts and times) for an individual horse as on any scientist's rational design of a flexible formula for all horses.Marketedformulas are based on sweat loss and changes in plasma.
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I inherited a number of processes, some of which were well established and effective and some where I could see they created more work for my team.
C1 esterase inhibitor (C1-INH) concentrate is well established as effective therapy for hereditary angioedema (HAE).
Solvent extraction is the well established cost effective operation for purification of vanadium in their aqueous solutions (Fornalczyk 2012 Marafi and Stanislaus 2008).
Although ionic liquids have been well established as effective solvents for the dissolution and processing of natural cellulose fibers, the detailed dissolution mechanism at the molecular level still remains unclear.
20, 23 Oral bisphosphonates are well established as effective first-line therapies for the management of PMO.
Local infiltration analgesia (LIA) is well established for effective postoperative pain relief in total knee arthroplasty (TKA).
It is well established that effective administration of single agent carboplatin may be compromised by dose-limiting thrombocytopenia, which may be circumvented by the platelet sparing effect of paclitaxel.
The role of family factors in self-harm is well established and effective prevention efforts need to balance the importance of respecting autonomy and confidentiality for young people and while also managing adolescents' concerns that getting help for their self-harm may make things worse for them or their family.
Although the most effective treatment of LVDD in patients with type 2 diabetes is unknown, it is well established that an effective aggressive multifactorial approach indeed reduces micro- and macrovascular complications [ 24].
The neurochemical alterations in mania are less clearly understood, but it is well established that drugs effective in the treatment of mania are those that antagonize dopamine and serotonin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com