Sentence examples for well established disease from inspiring English sources

Inflammatory processes may be the predominant determinant of disability in early RA, with structural abnormalities leading to functional impairment in well established disease.

23 The Danish Cystic Fibrosis Patient Registry is another example of a well established, disease-specific registry.

Although most well established disease-related mutations are within protein-coding sequences, it is logical to assume that mutations within enhancers could similarly result in human disease.

MRI has gained increasing interest in recent years because it has been shown to detect erosive changes in RA earlier than conventional radiography [ 3] and to predict later erosive development in early as well as more established disease [ 8, 9].

Experiments were designed to test the hypothesis that CpG ODN treatment can prevent the age-dependent accumulation of tau and Aβ when started prior to pathology development, as well as in established disease.

It is well established that disease can affect the disposition of xenobiotics.

For example, BRCA2 and APC are well established dominant disease genes for breast/ovarian cancer and colon cancer, respectively.

It is well established that disease-specific questionnaires are more responsive to treatment effects than generic questionnaires that are designed to measure health-related quality of life across a wide variety of diseases [21].

The concept that nutrient excess can lead to cellular stress is now well established in diseases such as obesity, metabolic syndrome, and diabetes but less commonly considered in microbes, particularly those in intracellular niches.

This argument is well established in the disease transmission theory.

The role of MIE is well established in neuromuscular disease patients in chronic and acute settings but not as a routine in  critical care.