Sentence examples for well established current from inspiring English sources

Although the roles of the PI3K catalytic subunit in tumorigenesis is well established, current understanding of the function of PI3K regulatory subunits such as PIK3R3 is still limited.

"It is well established that current levels of pollution are shortening people's lives, on a population basis," Green said.

Metal complexes have shown interesting preclinical and clinical results as antitumor drugs and platinum compounds are well established in current cancer chemotherapy.

The Bipolar Spectrum (BS) remains under-recognized in clinical practice and its definition is not well established in current diagnostic guidelines.

Whilst the incidence of the α-proteobacterium Wolbachia is relatively well established, the current knowledge of other inherited bacteria is much weaker.

While natural language interfaces are powerful, intuitive and desired, it is well established that current technology does not make it possible for us to support unrestricted querying on all databases accurately [ 36, 37].

It is well established that current treatment guidelines for ITP from ASH (George et al. 1996; ASH 1997; George & Davidoff 1997) and the BSH (BCSH 2003) are based on expert opinion rather than evidence because of a lack of high-quality clinical trials and long-term outcome data.

So far, the link of joint degeneration and meniscal changes is well established, but our current knowledge is clearly insufficient to benefit patients with new therapeutic strategies.

Thus, we see no reason to deviate from the fairly well established view that current machine predictors are neither poor enough to fail the usefulness criterion (RMSE around 1.8 log S units in this study), nor good enough for their achievements to be limited only by the uncertainty in experimental solubility data (RMSE approximately 0.6 0.7) [9].

The association between the GSTM1 null genotype and asthma development is not well established in the current literature.

Histologic classification have been well established by the current World Health Organization, which is almost identical to the paradigm implemented by Enzinger and Winslow [ 15].