Sentence examples for well established checkpoint from inspiring English sources

Taken together, these data suggest that in addition to its well established checkpoint and DNA repair functions (Cantor et al., 2001; Hiom, 2010), FancJ also plays an important role in centrosome biogenesis.

Lastly, we find that several well established mitotic checkpoint signaling components are also transported off kinetochores in the presence of NDGA.

In addition to our newly established checkpoint, I used my flashlight for daily latrine inspections.

These results indicate that the replication checkpoint kinases Mec1 and Rad53 restrain DSB formation by limiting the activity of DDK, a role well established in the mitotic replication checkpoint.

It is well established that the spindle assembly checkpoint prevents cells from entering anaphase by inhibiting activation of the anaphase-promoting complex (APC/C) through sequestration of its co-activator, Cdc20.

Officers have gone undercover as livery drivers and established checkpoints where they regularly stop drivers if they suspect a problem.

Soldiers, backed by tanks, established checkpoints on the main roads, while side streets were blocked by skips and shopping trolleys.

The implication of cdc25C in cell cycle transit, checkpoint signaling and mitotic activation has been well established over a considerable period of time [11], [9].

These functions have an special interest due to, it is well established that mutations in genes involved in DNA damage repair or in cell cycle checkpoints are associated with tumor progression [ 55].

Although not tested directly, evidence is mounting that p53, in addition to its other well established functions, mediates the cell cycle arrest and apoptosis that follows the activation of the mitotic checkpoint.

It is well established that cell cycle progression is a tightly ordered and regulated process that involves multiple cellular checkpoints.