In terms of patient characteristics, it is well established that age is an independent prognostic factor, with worsening outcome associated with increasing age [76,89,90].
Well established documented age skeletal samples were used to identify the degenerative trends presented.
5 6 7 8 9 10 It is well established that age and sex inequalities exist in secondary prevention of cardiovascular disease, particularly for cholesterol lowering treatment.
It is well established that age is an independent predictor of a 'not for resuscitation' order [ 6- 8], and scenario-based studies of physician decision-making also identify age as an independent predictor of denial of admission to ICU [ 9- 11].
Indeed, it is well established that age is a main risk factor for both AF and thrombosis [ 37] and our BNP-treated rats far exceeded life span of all their untreated littermates reaching a significantly older age than controls.
It is well established that age influences cognitive performance, with children performing worse in neuropsychological tests than adolescents and adults (Addamo et al. 2007) on tasks that are relevant to ADHD (Rommelse et al. 2008a).
Several BC risk factors are well established: high age at first birth (AFB), low parity (Ma et al, 2006), hormonal replacement therapy (Porch et al, 2002; Tjonneland et al, 2004), high body mass index (van den Brandt et al, 2000; Ahlgren et al, 2004), and high alcohol consumption (Boyle and Boffetta, 2009).
The neighbourhood differences in ideal ages for parenthood are already well established by ages 9 11, which concurs with recent evidence that, though interventions in adolescence tend to have no effect [49], those acting earlier in childhood may do so [50].
It is well established that age-related cognitive decline is a normal part of the ageing process that occurs across many cognitive functions including memory, orientation, attention, abstract thinking and perception.
It is well established that age-related bone loss occurs in men and male SD rats.
