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B-lymphocytes can be easily isolated and activated by well established activation protocols [14].
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Since it is well established that activation of Kv1.5 channel currents shortens an effective refractory period, GGA-induced activation of IKur or Ito may lead to atrial fibrillation as well as ventricular arrhythmia.
It has been well established that activation of HSCs plays a key role in the development of cirrhosis [1].
It is well established that activation of AMPK is associated with inhibition of the m-TOR pathway leading to ribosomal protein S6 dephosphorylation [27].
Cross-talk among the Rho GTPases has been well established, where activation of Cdc42 and Rac1 causes down-regulation of Rho.
In animal models, it is well established that activation of reward pathways provides both a strong influence on food choice [29], [30] and feeding behavior [31], associated with an increase in dopamine release in the NAc [32].
It is well established that activation of inflammatory cells determines the severity of pancreatitis.
It is well established that activation of Myc leads to enhanced cell proliferation but can also lead to increased apoptosis.
It is well established that activation of T-cell requires the formation of these structures [ 31, 36, 37].
It is well established that activation of insulin/IGF-1 receptor signaling exerts cardioprotective action [ 29- 31].
It is well established that activation of oncogenes can lead to ROS production [ 51], and ROS is an established source of endogenous double-strand breaks [ 52].
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CEO of Professional Science Editing for Scientists @ prosciediting.com