Sentence examples for well documented importance from inspiring English sources

Thus despite the well documented importance of p38 MAPK signaling in regulating hypertrophy of cultured smooth muscle cells, p38 MAPK does not appear to be part of a physiologically relevant signaling pathway in rat aortic smooth muscle.

Apart from the well documented importance of herd size as a measure of pastoral performance (see main text), the use of growth rates is problematic also because: (1) a negative relationship between compensation and growth rate would only indicate that the growth rate decreases, not that there is no growth.

The importance of both taxon sampling and model choice to the accuracy of phylogenetic studies has been well documented; however, the importance of the treatment of missing data has been examined less frequently.

The case of unconfined flames is less well documented but of importance in practical systems used in heating and drying.

Yet, despite well documented [ 3- 9] importance of surgery to improve psychological distress and self-esteem in patients with PE, the psychosocial status has not been systematically studied in patients who are not currently undergoing surgical treatment.

Reviewer 2: This is a very well designed study documenting importance of LRP4 in central nervous system and especially for long-term plasticity, learning and memory.

The important contributions of these products in meeting human dietary requirements for energy, high quality protein, and several key minerals and vitamins are well documented, though the nutritional importance of dairy fats is often less well understood.

Despite the well documented evidence on the importance of adequate weight management [ 8] as well as blood pressure [ 9, 10] and lipid control [ 11- 14], gaps currently still exist as evidenced by the large proportion of patients who are obese, with suboptimal blood pressure control and abnormal lipid levels.

Despite a well documented literature on the importance of the role of the informal care provision in LTC systems and his economical effect on LTC expenditures, it should be notice that Japanese LTCI system -based on universal entitlements - does not consider any payment mechanism for family caregivers.

Moringa oleifera (Saijan or drumstick), a cosmopolitan tropical, drought-tolerant tree, available throughout the year, has been well documented for its various pharmacological importance, viz., its analgesic, antihypertensive and anti-inflammatory effects (Joshi et al. 2012).

Further, the association between mortality and poor cognitive function is well documented (Langley 1995) suggesting the importance of understanding and recommending appropriate end-of-life care for people living with Alzheimer's and Huntington's disease.