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Aiming to solve the instability problem observed in the conventional RPCM using local nodes, a simple and yet effective procedure that uses the well-known least-square technique in a carefully designed manner has been proposed to restore the stability.
Despite the fact that not 100% of the mutant sequences were expected, TALEN-induced GSV was observed to work in a more precise manner after introduction of well designed ssODN.
His natural simplicity of manner and plethora of folksy sayings were well designed to avoid offending (as far as possible) republicans.
To verify our hypothesis that introduction of a well designed ssODN will guide the targeted GSV into a more precise manner, two ssODNs (B702-DE and B702-IN, Additional file 1: Table S2) were designed and synthesized.
They're well designed.
Runtastic.com is well designed, too.
Was the experiment well designed?
You know, practical, well designed, commercial.
The app is generally well designed.
The site wasn't well designed.
It was so different, so well designed.
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