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Although this model has limitations as a model for RA, as is evident from its independence from an autoimmune pathogenesis of arthritis, it nonetheless allows study of synovial changes provoked by a single, well defined trigger, namely TNF.
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Therefore, the study deliberately included a broad range of well defined triggers based on clinical and research experiences, as well as on the literature review and record review experiences, with the aim of validating these in a patient sample.
The states of a resource should be well defined to trigger a call to the API by the resource provider.
Cytochrome c has a well defined role in triggering apoptosis and as a marker of apoptosis [ 19], though it was recently shown that cytochrome c exists in a complex in serum with leucine-rich alpha-2-glycoprotein-1 which altered immunoreactivity [ 20].
Whereas the part of the trigger loop that interacts with the NTP was well defined (residues 1078 1083), the part of the trigger loop facing away from the NTP remained mobile (residues 1084 1092).
Intelligent tutors are developed by modeling and tracking a set of well defined tasks, whereas help agents are triggered by specific user or system events.
There are multiple factors for the development of delirium, the predisposing and triggering factors being well defined.
However, the intermediate signaling of adenosine that may be responsible for triggering exercise cardioprotection is less well defined.
Away from these regimes, well defined slanted modes and longitudinal modes can also be triggered.
Yet molecular triggers of EndMT have not been well defined.
While evacuation orders are generally given when life or property is immediately threatened, public health advisories to limit exposure are more problematic because the trigger point for taking action is not well defined.
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CEO of Professional Science Editing for Scientists @ prosciediting.com