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Is there a well defined question?
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While many of the major green plant clades are well defined, questions remain regarding the relationships among them.
This then explains why even researchers with a very well defined research question will have the irresistible urge to keep on digging for the answers to their newfound questions.
A well defined causal question stemming from a theoretical framework that is presumably of interest to governing bodies responsible for policy priorities.
Unfortunately, the risk factors leading to infection and nonunion when managing these types of fractures with this sequence of fixation are not well defined and the question on the best time to convert an external fixator to an IM nail remains unanswered [13, 14].
The use of thromboprophylaxis is uncontroversial in high risk situations such as major joint surgery in hips and knees but less well defined, and sometimes questioned, for many other non-major orthopaedic procedures [ 2].
Considering these two points, this study answers only well defined parts of the question about the comparison of AJCC-7 with AJCC-6.
As Dudoit and van der Laan [8] have shown, the first question is well defined with larger samples in V-fold cross-validation.
A study of Hong and Page also shows that group heterogenity beats individual ability, at least if the research question is well defined [30] (the best answers are obtained if the group does consist mainly of experts but there is a high heterogenity in their fields of expertise).
This is so when the questions concern well defined events that relate to respondents' lives (see for example evidence cited in Manski 2004; van der Klaauw et al. 2008).
As some groups were not previously sufficiently well defined, and would have been questioned by many microbiologists much more strongly than is now likely with the additional evidence adduced here for their monophyly, providing such evidence was essential.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com