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This mode of indirect trans regulation may be the most common form of gene regulation but also the hardest to detect except in well defined genetic backgrounds such as congenic mice.
By contrast, animal models represent genetic systems with well defined genetic background where tumorigenesis is initiated by known molecular events.
Although not well defined, the natural background concentration level of PAN is very low [3] so it is considered very specific indicator of anthropogenic photochemical air pollution; on the contrary ozone has relevant sources in stratosphere [10 12] where its level is high.
DOI: http://dx.doi.org/10.7554/eLife.09275.019 2) The aims of the study are well defined and the background is solid however I would add the following references.
2) The aims of the study are well defined and the background is solid however I would add the following references.
The matrix may partially absorb the stains making the distinction of cells from the background less well defined.
(Galison, 1997, p. 22) "The golden event was the exemplar of the image tradition: an individual instance so complete and well defined, so 'manifestly' free of distortion and background that no further data had to be involved" (p. 23).
The mean saliency value of the background is zero even in precontrast images because the kidney due to its well defined structure and edges is more salient than the background.
Necessity for a soft approach occurs with multi-levels images and whenever the separation between object and background is subjective or not well defined.
It is particularly remarkable how this effect makes the edges of cell and nucleus well defined and readily visible in comparison with the background.
'In the past, selection was not transparent, neither was it particularly well defined - do we need someone with a marketing or technical background?
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CEO of Professional Science Editing for Scientists @ prosciediting.com