Sentence examples for well characterized roles from inspiring English sources

SR proteins have well characterized roles in both constitutive and alternative pre-mRNA splicing.

The cytoskeletal protein actin has well characterized roles in many aspects of neuronal development and function from growth cone dynamics to the remodeling of dendritic spines [1], [2].

There are other examples of genes conserved between flies and vertebrates, that despite having well characterized roles in vertebrates, appear to have elusive functions in flies.

Of note, BPI and LBP play well characterized roles in sensing and responding to Gram negative bacteria, mediated primarily through their ability to bind the Lipid A region of the bacterial cell wall component lipopolysaccharide [19].

In comparison, miR-21, miR-181 and Let-7 have well characterized roles in cancer and it is not surprising therefore that their target genes result in enrichment for cancer-related pathways as well.

Ccr5, which mediates leukocyte attraction via chemokine receptor signalling, plays well characterized roles in inflammation [ 38].

The data reported here provide evidence that the function of the tegument extends from its well characterized role in nutrient uptake to include waste metabolite excretion.

These data extend the proposed functions of the tegument from that of its well characterized role in nutrient uptake to that of waste metabolite excretion.

IL-6 was chosen for further investigation to determine the signaling pathway that may underlie altered expression based on its well characterized role in hematopoiesis.

In contrast to the well characterized role that eosinophils play in the immunobiology of schistosomiasis and filariasis [51], [52], their role in the immunobiology of leishmaniasis has not been studied as extensively.

While the specific function of NEMO in relation to TNFα receptor stimulation is its most well characterized role to date, a growing body of work points to a far more variable role.