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miR-21 is a well characterized example of an oncogenic miRNA.
In this regard, autoimmune encephalitis (AIE) is a well characterized example of CNS autoimmunity suitable for further investigation of the specificity of MRZR.
Recognition of HIV by DC-SIGN is a well characterized example of the detrimental effect of CLR signalling in response to a virus.
Hormesis predicts that exposure to low levels of stress can result in favorable biological outcomes such as increased resistance to stress or extended lifespan; caloric restriction is a well characterized example of this phenomenon [ 38, 39].
One well characterized example of a such a stabilizing element is a 21-bp fragment of the φ10 promoter of bacteriophage T7 which can potentially form an 8-bp stem loop [ 28, 29].
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In order to compare and contrast PEV and TPE, we chose two well characterized examples of each phenomenon.
These studies have provided several well characterized examples of variants of αGalCer that have the ability to skew mouse iNKT cell responses to either pure Th2 cytokine production and immunosuppressive activity or predominantly Th1 cytokine production and pro-inflammatory activity.
There are several well characterized examples of Alu insertions affecting splicing patterns and hence protein function [ 12].
Herein, we follow this approach and focus on the lux01 and lux02 constructs as well characterized examples of the behaviour of the wild-type operon.
We note that the 5'- untranslated region is the locus of many well characterized examples of post-initiation transcription regulation, and that early elongation pausing is emerging as a theme in both prokaryotic and eukaryotic transcription.
Several means of regulation of protease activity have been well characterized, examples of which include sequestration of proteases through compartmentalization, such as caspases, proteasome, and lysosomal proteases, and conversion of precursor enzymes to active forms through zymogen activation, such as digestive enzymes like trypsin and chymotrypsin, and reversible posttranslational modification.
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