The Nkx6.1 homeodomain transcription factor is a potent transcriptional repressor with a key role in β-cell differentiation [ 81, 82] and has also been shown to suppress the expression of glucagon to maintain β-cell identity, as well as being able to regulate glucose-sensitive insulin secretion [ 83].
However, cells are able to regulate gene expression (gene regulation) as well as to modify proteins after translation from the genome.
This effect is independent of hematopoietic and other cells as well as inflammatory cytokines suggesting that epithelia are able to regulate their integrity in an autonomous non-inflammatory manner by sensing microbes directly via TLRs.
Results show that hornets and wasps are able to regulate their body temperature quite well, even during flight.
Newborns are also able to regulate their mother's attention as well as the initiation and maintenance of breastfeeding [10], [12], [13].
In their turn, T regulatory cells (Tregs), which are induced naturally or by elements of innate immunity are able to regulate all types of adaptive immune responses as well as influence DCs activation and regulation [ 94, 95].
The three-dimensional host framework with well-defined architecture acting as current collector has been proved to be able to regulate the lithium plating/stripping behavior and thus to suppress the dendrite growth.
The control law, which is able to regulate and to track the desired reference signals, is designed using the well known variable structure theory.
Moreover, CUX1 not only was able to regulate the next adjacent gene, but also regulated the gene located beyond this one as well as the gene located further away in the opposite direction.
Such a system must also be able to regulate the flow and consumption of matter and energy in order to facilitate self-constructive processes, as well as exchanges of material and information with the surrounding environment.
