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Body weights of animals were measured throughout the study but no significant differences between the treatment groups were observed (data not shown).
The weights of animals fed a normal chow diet were monitored from 3 weeks of age.
There were no significant differences in the weights of animals in the above various groups.
Body weights of animals were recorded at days 3, 7, 14 and 21 of age.
Phenotypic data for muscle weights of animals sampled for this experiment (Figure 2) show the characteristic muscle hypertrophy responses that have been previously reported for callipyge lambs [1] [3].
However the spleen weights, but not total body weights, of animals vaccinated with Ad5-prime/MVA-boost prior to high dose infection (Figure 2: Experiment 3A) were significantly lower than those in either vector only (p = 0.0003) or saline (p = 0.0205) sham vaccinated animals.
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STZ caused an abrupt decrease in body weight of animals.
c Change in the body weight of animals as a function of time.
For analysis, brain uptake (Bq/L) was normalized to injected dose and weight of animals.
Table 2 showed the changes in weight of all animals during the experiment as well as the lower weight of animals in the S5-treated group.
h The ratio of wet/dry lung weight of animals in both groups was calculated by gravimetric method.
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