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Gender related differences in body weight, physiology (e.g. pregnancy) or endocrinology (e.g. menstrual cycle) may affect PK.
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Additional analysis, not reported in [ 1], shows that out of admission type, age, gender, weight, Acute Physiology and Chronic Health Evaluation (APACHE) score, Simplified Acute Physiology Score (SAPS), cardiopulmonary resuscitation, and length of stay, only SAPS was a confounder.
Having established that wild-type and ob-norm animals have a similar body weight and physiology when maintained on the same diet, other than a modest impairment of glucose metabolism among ob-norm animals on a high fat diet, we next tested whether long-term exposure to a high- or low-fat diet affected the leptin sensitivity of these two groups.
Baseline data (age, gender, weight, Acute Physiology and Chronic Health Evaluation (APACHE II) and Sequential Organ Failure Assessment (SOFA) at Day 1) were recorded.
Demographic data, including age, sex, height, weight, Acute Physiology and Chronic Health Evaluation (APACHE) II score and admission diagnosis were recorded prospectively.
For each detected prescribing issue, the ICU hospital pharmacist recorded the date, patient characteristics (age, sex, weight, Acute Physiology and Chronic Health Evaluation (APACHE) II score calculated by the PDMS, and admission type (acute or elective)), medication details and the pharmacist's recommendation.
The goal was to determine how inadequate sleep over just one week — similar to what might occur when students cram for exams or when office workers stay up late to meet a looming deadline — affects a person's weight, behavior and physiology.
Basic patient characteristics such as age, height, weight and Acute Physiology and Chronic Health Evaluation III score [ 20] were documented.
These groups differ not only in size and body weight but in physiology and metabolism as well [ 7].
The mean age, weight, and Acute Physiology and Chronic Health Evaluation (APACHE) II scores of the included patients were 58 years, 84 kg, and 22, respectively.
A relationship between plasma PYY and CCK, body weight, APACHE (acute physiology and chronic health evaluation) II score, and length of ICU stay was assessed using Pearson's correlation.
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