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For PISwap, the ratio of α to can be thought of giving the relative weight of sequence information to topology information.
Parameters α and β(=1− α) control the relative weight of sequence similarity (scaled by α) as compared to topological conservation (scaled by β) in the BP network alignment.
Suppose the procedure assigns α i as the weight of sequence i, we can redefine p j (x), p k (y) and p j, k (x, y) as follows: (7) (8) (9) Entropy, joint-entropy and mutual information can then be calculated using these new definitions of probabilities.
Similar(57)
It is concluded that the change in the degree of blockiness caused by the solid-state polymerization of copolyesters is dependent on the molecular weight of sequences of the PET moiety in the structure.
Proteolysis was initiated with a 1 25 ratio (by weight) of sequencing grade modified trypsin and allowed to proceed overnight at 37°C.
The sequence tab also provides the Uniprot accession numbers, molecular weight, length of sequence and when available the structure.
The ratio of hydrophobic/hydrophilic groups in the copolymer and the molecular weight of each sequence were varied in order to establish the influence of these parameters on the interactions between the components.
Within each well, the minimum molecular weight of a sequence was 4567 daltons, and the maximum weight was 8949.9 daltons (Additional File 1).
AmyloidMutants sequence/structure landscapes were calculated permitting these four residues to mutate to Gln ('HET-s/4N→Q'), and the likelihood and corresponding energetic weight of each sequence within the ensemble was compared.
Previous studies on ferric reducing antioxidant power (FRAP) of enzymatic proteolysates concluded that the reducing power activity was related to some factors including size and molecular weight of peptides, sequence of amino acids in peptides, number of hydrophobic amino acid, and amount of sulphur containing and acidic amino acids.
Columns in the alignment that contain more than 80% gaps were excluded and the weight of each sequence was adjusted to represent its cluster size in the alignment thus reducing the influence of identical or near-identical sequences in the calculation.
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