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This decrease in birth weight effect was not seen among infants born to women who were employed within the 2-mile radius.
Next, a dose dependent positive weight effect was observed during one month daily treatment for most compounds; only the highest dose of insulin NPH and IGF1 caused a weight loss compared to control (Additional file 1: Figure S2).
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Low birth weight effect is not that evident.
The weight effect is the design effect due to weighting and is equal to 1 + C W 2, where C W is the coefficient of variation of the weights (i.e. the standard deviation of the weights divide by the mean of the weights) and is a standardised measure of the variation of the weights.
Although the birth-weight effect was slightly larger in women who started supplementation ≥3 mo before becoming pregnant, our results suggested that the intervention had similar efficacy irrespective of the duration of supplementation preconceptionally.
Birth weight effects are in logarithmic scale.
HbA1c and weight effects were maintained after 52 weeks.
Interestingly, although these ieQTL effects are very significant, the body weight effects are slight.
Although weight effects were modest, liraglutide produced more favourable weight effects compared with rosiglitazone, which produced substantial weight gain.
The weight effects were calculated using weff = n ∑ w i 2 (∑ w i ) 2 where: n denotes sample size and w denotes weights [ 20- 22].
It was however encouraging that the weight effects were similar to those found in the previous year, when only a landline based sample was used.
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