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In addition to body weight, dosing regimens should take into account the creatinine clearance.
Mice receiving 100 mg/kg body weight of plumbagin died within 4 8 days, whereas those receiving 50 mg/kg body weight dosing died within 8 11 days.
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It follows that in some patients with higher body weight, doses higher than the standard 400 mg are required.
We calculated ideal and adjusted body weights and dosing weights for antimicrobials as recommended [ 6, 27] [see Additional file 1, Appendix B].
The 300 mg/kg body weight dose was found to be more effective.
Clot resolution was not related to patient age or weight, dose, and duration of tPA therapy and fibrinogen levels.
In this children may be receiving antituberculosis drugs in doses which may be more or less than that recommended in mg/kg body weight doses.
Briefly, 30 min after NC, PC, LM100 and LM200 administration, thiopental sodium (at 40 mg/kg body weight dose) was administered to each rat to induce sleep.
On the other hand, 200 and 400 mg/kg per body weight doses of crude methanolic extract were administered i.p. to group III and IV as test samples.
In Study 2, four animals were challenged weekly with a lethal dose of LT combined with a similar weight dose of ET administered as 24 h infusions (Figure S1B in Additional file 1).
A single 0.5 mg/kg body weight dose of cadmium acetate was administered intratracheally.
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