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Adequate contrast opacification is critical for diagnostic quality, which depends upon patient weight, cardiac output, scan duration and contrast delivery protocol [11, 12].
The human dichloromethane PBPK model by David et al. (2006) specifically used a probabilistic description of model parameters such as body weight, cardiac output, and metabolic rates to describe a distribution of dosimetry among humans.
In contrast, physiology-based pharmacokinetics use a 'from physiology to clinical observations' approach; driven by characteristics of neonatal physiology (e.g. weight, cardiac output, renal function) and anatomy, as well as its age-related changes, a physiology-based pharmacokinetic model is developed [ 118– 118].
Using a modified APACHE-II-score 39 patients (group I) at high risk and 20 patients (group II) at low risk were identified on the first postoperative day after cardiac surgery on CPB and hypothermic (26°C) cardioplegic (HTK-solution, 4°C, 15 ml/kg body weight) cardiac arrest.
Data collected for enrolled patients included demographics, height and weight, cardiac history and other significant comorbidities, date of initial breast cancer diagnosis and stage, histology, hormone receptor (HR) and HER2 status, prior adjuvant or radiotherapy, and date of MBC diagnosis with sites of metastatic disease at diagnosis.
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Following were the manifestations studied: heart-to-body weight ratio, cardiac inflammatory score, cardiomyocyte diameter determination, and cardiac viral levels, as previously described [ 8].
To determine the incidence of postoperative airway complications in infants < 5 kg in weight undergoing cardiac surgery intubated with Microcuff (Kimberley-Clark, Roswell, GA) endotracheal tubes (ETTs).
The mechanisms responsible for lower birth weight and cardiac abnormalities in children exposed to cART are unclear but could be related to dysregulation of maternal amino acid metabolism during pregnancy.
The tTA/HSPB8/R120G triple TG mice showed decreased heart weight, improved cardiac function and reduced interstitial fibrosis as compared with those of R120G TG mice (Figure 5C F, Table 1).
Results were more divergent for the weight of cardiac atria, as average AWI of most strains was lower in the CV-PGX study than in Deschepper's data (Figure 3).
We found that the rates of increase in body weight and cardiac weights in the pigs were the same and were not sex-dependent.
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