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81 Again, this apparent weight benefit increased with baseline BMI.
Of the three therapies evaluated in this analysis, exenatide exhibited the strongest weight benefit, followed by sitagliptin.
In general, for studies in which insulin was aggressively titrated to optimize glycaemic benefits, there was less weight benefit of the combination therapy.
Meta-analyses found a weight benefit for metformin versus placebo of 5 kg [ 151], 3.2 kg [ 152] or 4.8 % [ 153] of initial weight.
Insulin glargine was infrequently titrated (6 8 week intervals) in this study and insulin dose was not significantly reduced during the course of the trial which may be related to the lack of weight benefit from the combination.
For obese, metformin-treated patients who fail to achieve the individualized target for HbA1c, second-line treatment choices in order of weight benefit would be: GLP-1 agonists, DPP-4 inhibitors, acarbose, bile acid sequestrants, and amylin analogs [ 7].
Similar(52)
Sandwich composite materials are characterized by high strength and low weight benefits.
"You can say, 'We offer weight management as part of wellness programs, and controlling your weight benefits you, the employee.
The aim of preference-based evaluation methods is to assess and weight benefits, costs and risks of therapy options with respect to the individual needs of patients.
Basic results for the weight benefits relative to solid plates are presented, with emphasis on restricted optimizations that assure robustness (non-catastrophic failure) and acceptable thinness.
Scepticism related primarily to the health and weight benefits of this diet in comparison with those of the present dietary recommendations in Denmark.
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