Exact(8)
Offspring born to dams fed control or P diet, when fed P diet exhibited a higher body weight, altered hypothalamic leptin sensitivity and metabolic parameters suggesting that maternal P diet has no protective effect on offspring.
Inoculated animals were observed for the development of signs of lethal plague disease, including loss of body weight, altered physical behavior and death, for a period of 10 days.
After 8 weeks, the obesogenic dietary regimen increased the body weight, altered the plasma lipid profile and increased the liver fat content and the plasma transaminase activities.
Adverse effects include reduced birth weight, altered fetal cognitive and reproductive tract development, and increased risk of premature birth and spontaneous abortion.
This is especially relevant because in addition to a low birth weight, altered immune reactivity in neonatal pigs is associated with a greater risk of postnatal mortality, a major concern with regard to animal welfare [ 21, 22].
Perinatal exposure to BPA at 0.1 or 1.2 mg/kg body weight (bw) per day through drinking water significantly increased body weight, altered estrous cyclicity, and significantly lowered plasma concentrations of luteinizing hormone (Rubin et al. 2001).
Similar(52)
CdCl2 increased the height of the uterine luminal epithelium in a dose-dependent manner without increasing the uterine wet weight, altering the timing of vaginal opening, or affecting the luciferase activity in reproductive or nonreproductive organs.
Finally, the additional inclusion of non-response weights altered the revealed estimates only slightly (data not shown).
The reduced body weights, altered soft tissue composition, and increased metabolic rate in the male TG mice presented here are hallmarks of the cachectic state in humans.
The simplified score was generated using the following indicators and weights: jaundice (weight, 1.0); subcostal indrawing (weight, 1.0); prostration ± seizure (weight, 2.0); altered consciousness (with seizures, weight, 2.0; without seizures, weight, 3.0); wasting (weight, 1.0).
Excess weight alters levels of hormones and growth factors.
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