His apparatus for weighing the world was a modification of the Englishman John Michell's torsion balance.
Decisions regarding design modifications are based on weighing several factors such as technical and economic feasibility, overall functionality and structural rigidity of the product as a whole.
Although for single-dose use, weight-based dosing seems unnecessary, dose modification is needed in subjects weighing more than 110 kg if oritavancin is used in multiple doses.
Essentially a test aircraft designed for easy and rapid modification, the VS-300 was small (weighing 1,092 pounds) and was powered by a 65-horsepower Lycoming engine.
By following previously described method with slight modification [ 30], 12 16 h fasted mice (weighing 20 25 g, n = 84) of either gender were housed in cages in fourteen equally divided groups (n = 6).
Eighteen yearling sheep weighing 27.5 ± 0.4 kg were instrumented, as a modification to previously described techniques [ 16- 19], by inserting introducers into the left external jugular vein and common carotid artery.
Rat cortical synaptosomes were isolated from the cortical tissue of male Sprague-Dawley rats (Taconic Farms) weighing between 180 and 230 g according to [44] with modifications described elsewhere [45].
In June 2016, a Diabetes Care Editors' Expert Forum convened to review the processes and challenges of CVOTs, discuss the benefits and limitations of their current designs, and weigh the merits of modifications that might improve the efficiency and clinical value of future trials.
Better carriers are now being sought to reduce the laborious and time-consuming modification of carrier surfaces, to eliminate errors that arise during weighing of the silica gel, and to eliminate adsorption of contaminants by the surface [ 11– 13].
Lawmakers are weighing legislation that could help borrowers reduce their debt burdens, either through bankruptcy, government-sponsored modifications or refinancing schemes.
Third, regular weighing may help patients address two problematic behaviors with a negative influence on lifestyle modification adherence: excessive weight checking and avoidance of weight checking.
