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Women who were between the gestational ages of 10 and 18 weeks were randomized from three clinical centers across the United States — Boston Medical Center, Washington University in St . Louis and Kaiser Permanente Southern California Region (San Diego, CA).
Eligible patients with OIC (n = 207), defined as <3 spontaneous bowel movements (SBMs) per week with accompanying symptoms, on a stable opioid regimen of 30 1000 mg/day morphine equivalents for ⩾2 weeks were randomized to receive 4 weeks of double-blind placebo or naloxegol (5, 25, or 50 mg) once daily in sequential cohorts after a 1-week placebo run-in.
Study Design: In this double-masked, controlled clinical trial, pregnant women with diabetes and gestational age of >38½ weeks were randomized to receive 25 μg misoprostol or placebo vaginally on days 1 and 4 of a 7-day outpatient cervical ripening period.
Study Design: One hundred fifty-seven pregnant women with a singleton live gestation, Bishop score of <7, estimated fetal weight of <4500 g, and gestational age of >24 weeks were randomized to receive misoprostol that would be placed either in the buccal pouch or vagina every 6 hours.
Patients with stable disease at 12 weeks were randomized to either continue pazopanib or a placebo.
Male C57BL/6 J mice, age 8 12 weeks, were randomized into four groups: vehicle, DDFPe, 5-HD + vehicle, and 5-HD + DDFPe.
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Workers still on sick leave at 8 weeks are randomized for the Graded Activity intervention.
Adults with opioid-induced constipation (OIC; <3 spontaneous bowel movements [SBMs] per week) were randomized 1 1 to double-blind lubiprostone 24 μg or placebo twice daily for 12 weeks.
Heimstad conducted a trial where women in the 41st gestational week were randomized to a waiting group or an induction group and asked about their attitudes towards post-term pregnancy [ 7].
Adult participants (n = 400) with LE OA, age 60 +, overweight/obese, and not meeting PA requirements of ≥ 150 min per week, are randomized to one of the two programs.
After 2 weeks, subjects were randomized to 2 additional weeks of concomitant budesonide aqueous nasal spray (n = 9) or placebo (n = 10).
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CEO of Professional Science Editing for Scientists @ prosciediting.com