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Exact(31)
Tacrolimus and ciclosporin could not be used in the 4 weeks before screening.
All permitted previous anti-HCV therapies must have been completed or discontinued at least 12 weeks before screening.
Patients were excluded if they had been treated with insulin, peroxisome proliferator activated receptor-γ agonists, glinides, or glucosidase inhibitors within the last 4 weeks before screening.
Subjects had no other lung disease, no self-reported lower respiratory tract infection or worsening of asthma for 8 weeks before screening.
The arbitrary 2-month cutoff was made on the basis that patients' symptoms might still be affected by treatment such as chemotherapy, completed several weeks before screening.
Patients had used inhaled corticosteroids (ICSs) daily for ≥ 30 days before the screening visit and were on stable ICS doses for ≥ 2 weeks before screening.
Similar(29)
Patients who had not taken any phosphorus binders for 1 week before screening could skip the washout period.
Patients with a history of systemic corticosteroid use within the previous 3 months, omalizumab use within the previous 6 months, or leukotriene antagonist use within the week before screening, were also excluded.
The main exclusion criteria were use of OADs other than a sulphonylurea or metformin within 3 months prior to screening or use of insulin for ≥1 week within the 6 months before screening.
Instead, pre- and postscreening measurement took place 2 months before and 1 4 weeks after screening.
Consent forms, questionnaires and information sheets were distributed to the parents two weeks before the screening procedure.
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