Based on this, preemptive antiviral therapy (ganciclovir [5 mg/kg, bid] or valganciclovir [900 mg bid] with dose adjusted for renal function) was initiated when the viral load exceeded 3000 genomes/mL with the aim of preventing the viral load from reaching 37 000 genomes/mL, taking into account the average doubling-time of 1 day (13) and the twice-weekly timing of sampling.
By superimposing a weekly time series of rates for each of the 13-seasons individually, the variability in annual weekly intensity and peak timing is evident (Figure 3).
All estimates are adjusted for possible confounders in terms of calendar year, weekly working hours, timing of transition to parental leave and marital status, but for simplicity these control variables were left out of the analysis.
The two made weekly phone calls to schedule the timing of the leaks.
23 October 2009 Moir publicly apologises to Gately's family and friends for the timing of her comments in her weekly Daily Mail column the following Friday, but also insists she did not hold "poisonous" homophobic views.
The timing of sampling depended on the season with weekly sampling occurring during spring, summer and autumn and fortnightly sampling occurring during winter.
However, the focus of previous studies was comparing the timing of dosing (i.e., daily versus weekly versus monthly).
13 14 Shrestha et al 14 also assessed binge drinking episodes during pregnancy, but found no effects on the timing of menarche, either of binge drinking or of weekly alcohol consumption.
At our institution, the attending physicians on the MTU are expected to incorporate a mandatory once-weekly medical teaching team rounding session into their schedule, the timing of which is at their discretion.
Stephen Pollard, the editor of Britain's Jewish Chronicle, a weekly newspaper, said in a BBC radio segment on Tuesday that the timing of the cartoon was "grotesque".
Publishers Weekly called him, "an indescribable amalgam of Dave Barry, Jim Murray, and Lewis Grizzard, with the timing of Jay Leno and the wit of Johnny Carson".
