Sentence examples for wealth of binding from inspiring English sources

As a consequence of the wealth of binding modes, the molecular architectures observed for cobalt II) complexes of carboxylate ligands are extremely rich and varied.

New approaches, namely phage display [ 7], protein or peptide arrays [ 8- 10] and oriented peptide libraries [ 11] have greatly facilitated the measurement of specificities and produced an hitherto unimaginable wealth of binding data.

It leverages the growing wealth of binding data between PRDs and large numbers of random peptides, and searches for PRD residues that exhibit strong evolutionary covariation with some positions of the statistical profiles of bound peptides.

It uses the wealth of sequences (binding peaks) usually resulting from ChIP-seq experiments to both predict motifs de novo, as well as validate these motifs in an independent fraction of the dataset.

These families tend to be those where the enzymes are both druggable and widely studied, or were a single initial drug compound has been developed into many derivatives, leading to a wealth of compound binding information being available for them.

Additionally, the ENCODE Project Consortium (2012) (a high-profile effort to build an encyclopedia of coding DNA elements) has generated a wealth of DNA-binding information that can be used to generate priors on mammalian regulatory network structure.

A wealth of nuclear receptor binding data has been generated by the application of chromatin immunoprecipitation (ChIP) techniques.

Furthermore, the wealth of novel AtoC-binding sites, some of which are present within gene-encoding sequences, should be further analyzed for their functional significance in gene regulation.

In the past decade, characterization of a variety of calcium binding proteins provides a wealth of information about how Ca2+ binding to their individual EF-hands leads to biological responses.

The BIND-descr object contains a wealth of information, including experimental conditions (BIND-cond), sequence conservation information (BIND-cons), binding sites (BIND-binding sites), binding actions (BIND-action), binding states (Bind-state-descr) and cellular compartments (BIND-place).

Deep surveying of alternative splicing by RNA-seq revealed unprecedented wealth of splice junctions and RNA-binding motifs and provides more reliable measurements compared with microarray technology.