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Luciferase reporter assays that use single copy response elements are sometimes weakly responsive to transcription factors.
Interestingly, genes strongly induced or repressed in the 'acd11 response' were either nonresponsive or only weakly responsive in acd11/nahG/laz1-1 acd11/nahG/laz1-1
For instance, pairing a weakly responsive sound with a sound that evokes strong responses with a short inter-stimulus interval induces a shift in auditory cortical frequency tuning in ferrets, and activation of the cholinergic system promotes this plasticity.
Further, non-responsive wells in the GN2 plates were weakly responsive (in terms of all kinetic parameters) in the GN plates.
More importantly, this receptive field heterogeneity played a major role in the integrative product exhibited by stimulus pairings, such that pairings at weakly responsive locations of the receptive fields resulted in the largest multisensory interactions.
Leptin-resistant obese animals and patients are weakly responsive or unresponsive to exogenously administrated leptin.
Similar(41)
We previously identified MYBR1 as a weakly ABA responsive gene [ 14] and here we provide evidence that it is a repressor of ABA signaling during seedling growth, drought and senescence.
Comparative transcriptome analysis of salt-tolerant and salt-sensitive genotypes indicated that essential salt tolerance-related genes and miRNAs were differentially expressed and were only weakly or non-responsive to salt stress in the salt-sensitive cotton.
Our genome-wide analysis demonstrates that previously proposed elements, such as promoter TATA boxes [ 18], are only weakly associated with fasting-responsive CREB target genes.
These transfected cells were found to be weakly- or non-responsive to epidermal growth factor induced cell growth (Tian et al, 1999).
However, despite cultivation of the cells in phenol red-free medium and charcoal-stripped serum, every responsive clone revealed variable, weakly positive nuclear immunostaining for myc during passage in the absence of 4OHT.
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