By contrast, Gln-KPA inhibits E. coli glutaminyl-tRNA synthetase (GlnRS) by binding competitively but weakly at two distinct sites on this enzyme (average Ki of 0.65 mM); the non-cognate Glu-KPA shows one-site weak (Ki = 2.8 mM) competitive inhibition of GlnRS.
Considering that 25 distinct "weakly" protective or non-protective HLA proteins restricted almost 40 immunodominant CD8+ T-cell responses of the B*57/27neg LTNP/EC in the present study, the overall probability of carrying at least one of these alleles in the general population is quite high.
The results show that synthetic and phytoestrogens are weakly estrogenic but induce distinct patterns of ER agonist/antagonist activities that are cell context- and promoter-dependent, suggesting that these compounds will induce tissue-specific (in vivo ER agonist or antagonist activities.
The trunk is weakly trilobate, composed of 27 distinct tergites with well-developed pleural spines and a terminal piece.
Weakly restricted channel systems have distinct incised sections, and wedges (large natural levee deposit) are developed on both sides.
Rate and breadth are two distinct, and only weakly correlated, characteristics of protein evolution.
The nonpathogenic and weakly pathogenic strains are phylogenetically distinct from the G1 G6 strains with ≈20% of nucleotide divergence (7 ); they typically replicate in the intestines (8, 9 ).
Distinct from conventional weakly-guiding optical fibers, large longitudinal electric field (Ez) exists in wavelength-scale microfibers.
All are magnetic, although franklinite and jacobsite are only weakly so; magnetite, which frequently has distinct north and south poles, has been known for this property since about 500 bc.
Nevertheless, it is clear that most of the mandibles exhibit a distinct mental trigone, but generally with weakly developed or absent mental fossae and weakly developed, non-projecting mental tubercles.
