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The term aprotic has been extended recently to include solvents that are unable to lose a proton, although they may have weakly basic properties.
The first weakly basic condition benefits the formation of hydroxymethyl phenols at 313 K.
The weakly basic drugs were tested using USP apparatus I in 0.1N HCl buffer.
The m-АPAA molecule contains acidic groups of intermediate strength (−AsO3H2) and weakly basic groups (−NH2).
These enzyme inhibitors possess desirable physical properties that can be readily modified by incorporation of a weakly basic amine.
Precipitation of poorly soluble, weakly basic drugs upon entering the small intestine may lead to poor bioavailability.
For many decades, it has been known that weakly basic compounds can be sequestered into acidic organelles such as lysosomes.
Temperature- and pH-sensitive hydrogels were prepared by copolymerizing NIPA with weakly acidic and/or weakly basic monomers.
A macroporous, strongly basic anionite or a weakly basic gel were used to neutralize the HCl formed during the reaction.
the weakly basic constraint qualification (the (WBCQ)) at x ∈ A if ∂ ( f − g + δ A ) ( x ) ⊆ N ′ ( x ).
Incorporation of weak acids as pH modifiers enhances the release of weakly basic drugs in higher pH environments by reducing the microenvironmental pH (pHM).
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