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p300 was weakly active at Lys14 and did not reveal a strict dependence on distal sequence variation.
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The coexistence of functionally opposite marks in immature progenitors and in myelinating cell lines was indicative of a "poised", but inactive or weakly active transcriptional state at the myelin gene loci.
These enzymes were also only weakly active, giving 2 at levels lower than P411BM3-CIS-T438S (3–4 TTN).
Ethyl acetate was weakly active in [3] at the ab5B ORN but inactive in the original data.
Receptors truncated at aa 282 were either weakly active or inactive; however, an ER deletion at aa 351 was approximately 50% as active as wild type ER (induced with estrogen).
The dorsal putamen, bilaterally but weakly active in our previous study [1] at [−22, 0, 10] and [26, 0, 2], was not apparent in the contrast Loved > Neutral in this study.
Our compounds show potent activity at low doses whereas 2MeOE2 at the same low dose is only weakly active.
The first variant was only weakly active, had molten globular characteristics, and was monomeric at 25 °C despite being based on nearly all dimeric enzymes.
Remaining sites were considered as weakly active (weak splice sites).
Removal of the acetic acid moiety led to inactive or weakly active target compounds.
However, it is negative or only weakly active in standard in vitro genotoxicity assays.
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